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The height was measured in supine position with full extension of knee and distance between top of head and heel when pressed against a vertical surface and rolled on a stabilizing board by infantometer to the nearest 0.1 cm. Circumferences were measured by nonextendable measuring tape to the nearest 0.1 cm. Head circumference was obtained by placing tape along the largest occipitofrontal diameter along and over the occiput and eyebrow. The chest circumference was measured by placing measuring tape along the point of the nipples. Of the 200 infants in this study, 60 (30 males, 30 females) were measured twice to estimate measurement error. A mixed-model ANOVA was used to estimate repeatability of the asymmetry. In this method, the main fixed effect is sides (S; right or left). The block effect is individuals (I). The sides by individual interaction (S �� I) GPX4 is a mixed effect. An error term (m) represents measurement error (replications within sides by individuals). find more The ratio of the S �� I mean square to the residual (error) mean square provides an F-test of whether the estimated nondirectional asymmetry (i.e., fluctuating asymmetry and antisymmetry) is significantly greater than zero (Palmer and Strobeck, 2003). The variance component for the S �� I interaction is sometimes used to estimate fluctuating asymmetry and its statistical significance is determined by an F statistic testing the null hypothesis (Graham et al., 2010). The variance components Osimertinib purchase of the side-by-individual interaction terms were significantly greater than zero for all four traits (Ear length: F1,59 = 19.82, P