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It also tends to separate from the bone more readily. Though considered to have little tendency for recurrence, variable recurrence rates have been reported by variousauthors.8 Learning points Ameloblastic fibroma (AF) should always be kept in mind in younger age group patients presenting with orofacial Ruxolitinib swellings. Though AF is a tumour, it can be successfully treated with a conservative approach. Not every pathology needs aggressive treatment. Histologically the ectomesenchymal component of AF along with the relatively scanty stellate reticulum in smaller follicles as compared with ameloblastoma helps in differentiating these pathosis from each other. Footnotes Competing interests: None. Patient consent: Obtained. Provenance and peer review: Not commissioned; externally peer reviewed.""A 58-year-old man with a medical history of schizoaffective disorder, delusional parasitosis and clostridium difficile colitis (CDC) was hospitalised for worsening diarrhoea, as a result of CDC exacerbation. His physical examination revealed normal vital signs and a bluish-grey pigmentation of the skin and nailbeds (figure 1). The patient firmly believed that he had Morgellons disease (a form of delusional parasitosis). In the past, he had seen several physicians including psychiatrists to seek treatment for his delusional parasitosis. The patient reported that he had been using oral silver colloidal solution for several months, in order to purify his blood and kill the (delusional) parasites, which he believed were present in his skin and stool. He got introduced to this remedy through the internet. Review of his prior medical records revealed a negative diagnostic workup for Addison's disease and haemochromatosis, but a positive skin biopsy confirming the diagnosis of argyria. Figure?1 Demonstrates silver-grey discolouration of the face and nail beds. Multiple small scratches on his skin of the dorsal surface of his hands are seen (marked with arrows). These scratches were self-inflicted by the patient, and he firmly believed these ... Argyria is a rare disorder associated with the exposure or ingestion of silver compounds resulting in a permanent dermal deposition of inert silver salts and has no effective medical treatment.1 2 Unfamiliarity to this disorder may often result in a clinical misdiagnosis prompting unnecessary further work-up. Common disease conditions which may mimic argyria are cyanosis, Addison��s disease, haemochromatosis, Wilson��s disease, Ochronosis and methaemoglobinemia.1�C3 Skin biopsy revealing silvery granule deposits is considered a gold standard for the diagnosis of argyria, however is rarely required, as the clinical history and physical examination findings (including skin examination under fluorescent X-ray) are considered sufficient in routine practice.