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Furthermore, platelet sequestration is a possibility in GVMs and hence at least a full blood count and coagulation screen should be obtained. Histologically, GVMs are less well circumscribed as they lack the fibrous rim of their solitary counterparts. Their appearance is more representative of a haemangioma and they contain several, irregular, dilated vascular spaces that are larger than those observed in the solitary variety.3 They also have fewer glomus cells than the solitary form with narrow, focal aggregates of glomus cells in the walls of the Sucquet-Hoyer channels.4 This case is the first to follow-up a patient following excision of these lesions after 8?years. It is clear that recurrence is a possibility at previous sites of surgical excision while there is also the potential to develop new lesions elsewhere. As is evident from the number of possible differential diagnoses, GVMs may prove to a diagnostic challenge. However, awareness of this condition with an appreciation for its clinical presentation in the child, most often with a positive family, should make diagnosis less difficult. Learning points Glomuvenous malformations may prove to be difficult to diagnose clinically. However, the presence of multiple painful lesions at a number of different sites on the body together with a positive family history should alert the physician to the possibility of it as a differential diagnosis. Histologically, glomuvenous malformations display fewer glomus cells, have larger irregular blood vessels and lack the well circumscribed fibrous rim of their solitary counterparts. Although surgery maybe curative, there is the possibility of recurrence at the same site. Children are more commonly affected by glomuvenous malformations and lesions may continue to develop throughout life at various different sites on the body. Close follow-up is essential, especially as internal organ involvement may lead catastrophic consequences including metastases and acute gastrointestinal haemorrhage. Acknowledgments We would like to thank Ian Tryptophan synthase Wilkes, Pauline Kewell and the rest of the staff at The Warner Library for help with obtaining journal articles for this manuscript. Footnotes Contributors: SJ was responsible for conception of report and writing of the entire manuscript. QF edited the manuscript. MP was responsible for further corrections and providing pathology slides and figure annotations. PD was the operating surgeon and made final corrections prior to submission. Competing interests: None. Patient consent: Obtained. Provenance and peer review: Not commissioned; externally peer reviewed.""Peripheral neuropathy due to nerve compression is a rare complication of neurofibromatosis type 1 (NF1) described in up to 4% of all cases.1 Nevertheless, it can represent a severe complication of NF1 associated with frequent morbidity including the development of malignant peripheral nerve sheath tumours (MPNSTs).