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1�C3.0?mg/L, n=26), high (3.1�C10.0?mg/L, n=83) and very high (>10.0?mg/L, n=239) CRP categories. Statistical analyses Normally distributed continuous data are presented as the mean��SD and non-Gaussian distributed variables as the median (IQR). Categorical data are presented as sample number and percentages. For group comparisons, we initially used ��2 analysis with calculation of odds ratios (ORs) with 95% CIs presented were appropriate for discrete variables, and independent t tests for normally distributed continuous variables and Mann-Whitney U test for non-parametric continuous variables. Multiple logistic regression analyses (entry model) were used to derive age and sex adjusted ORs (and BMI in some analyses, as described) for the risk of presenting with clinically relevant variables Stem Cells inhibitor (primarily dyslipidaemia profiles), according to CD HD relative to NCD diagnosis. Significance was accepted at the two-sided level of p profile Table?1 shows the sociodemographic and clinical profile of this cohort according to cardiac aetiology. Those presenting with NCD (n=678, 56.5% of TAK-632 cohort) were older and had higher BMI and mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) than those with CD (n=521, 43.5%; all comparisons pSelleck Ipatasertib most prevalent primary diagnoses were HT-HF (n=461, 38%), DCMO (n=178, 15%) and CAD (n=157, 12%). In those classified as NCD, HT-HF was the main primary diagnosis (n=461, 68%), along with CAD (without concurrent HIV infection; n=157, 23%). DCMO (n=178, 34%), right HF (n=92, 18%) and right HD (n=63, 12%) and other forms of primary valve disease (n=71, 14%), were the most common diagnoses in those classified with communicable forms of HD. Lipid profiles Those with CD have significantly lower TC, LDLC and HDLC compared with patients with NCD (table 1 and figure 1, p