The actual Appeal Of Transducin

Data on hospitalization and any other antimicrobial treatment for the 3?months before the studied admission were collected, as well as information on co-morbididities such as diabetes mellitus, cancer, haematological, liver, respiratory, cardiovascular; urinary, nervous diseases, HIV infection and acute or chronic renal failure. For all patients included in the study, the time of mechanical ventilation, tracheal intubation, tracheostomy tube, placement of a Staurosporine order bladder or central venous catheter or nasogastric tube, and administration of parenteral nutrition was calculated. The Acute Physiology and Chronic Health Evaluation (APACHE) II score on admission to the ICU was calculated. The performance of invasive procedures such as bronchoscopy, nephrostomy, gastrostomy, colostomy, cystoscopy and placement of a pigtail catheter was noted. VAP was defined according to the criteria of the American Thoracic Society Consensus Transducin Conference on VAP; specifically, by the presence of: fever greater than 38��C with no other recognized cause; leucopenia (GSK126 solubility dmso variables, respectively. Variables significantly associated with the studied outcomes in the bivariable analyses were entered in a multivariable backward, stepwise, logistic regression model. For all tests, a two-tailed p?��0.05 was considered as statistically significant. The analyses were performed using the statistical software SPSS, version 15.0 (SPPS, Chicago, IL, USA). We identified 205 patients who received i.v. colistin for more than 3?days for a microbiologically documented infection during the period May 2005 to August 2007 inclusive.