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0); 92% were women, 60% were physicians, 33.3% were nurses, and 6.7% were social workers and clinical psychologists. Baseline measurements did not show significant differences between groups in age, occupation, and scores in any scale or subscale (TABLE 1). Attendance at the sessions was 92%. All participants completed the intervention and none of the participants missed more than 2 sessions. The following results were observed in the intervention group: Burnout decreased by 6.0 points (95% confidence interval [CI] �C10.4 to �C1.5), a small but statistically significant change (SRM 0.43). This reduction was also found in the subscales emotional exhaustion and depersonalization; Ritipenem personal accomplishment also improved. Compared with the control group, the intervention group decreased by 7.0 points (95% CI �C13.4 to �C0.6), with moderate effect size (SES 0.74) (TABLE 2). Mood disturbance decreased by 6.5 points (95% CI �C9.8 to �C3.3), CB-839 clinical trial a moderate change (SRM 0.62). This reduction was also observed in the following subscales: depression, anger, tension, and fatigue. There was no significant change in the vigor subscale. The intervention group decreased by 7.1 points (95% CI �C11.3 to �C3) (p PLK inhibitor (95% CI: 0.2 to 10.3), with moderate effect size (SES 0.71) (TABLE 4). Mindfulness increased by 12.0 points (95% CI 6.0 to 18.1), a moderate change (SRM 0.65). Except for describing, all subscales improved. When compared to the control group, the increase was 11.0 points (95% CI: 3 to 19), with large effect size (SES 0.90) (TABLE 5). No significant differences in any of the scales were observed in the control group. When participants in the intervention group were asked to evaluate the program, all reported feeling better after the intervention: 87.8% felt that their overall energy had increased, and 65.7% reported improved activity levels; 76% indicated attitude changes, and up to 44.7% manifested an improvement in ��taking care of oneself��; and 87.2% of the participants reported to have learned coping strategies during the program, such as communication and time-management skills, handling stressful situations, and correction of bad habits. The program was rated 8.9 on a scale from 0 (low) to 10 (high). Self-reported adherence to mindfulness exercises was high: 85.1% practiced contemplation-meditation for 30 to 45 minutes with a CD regularly at the end of the intervention, 70.2% used breathing awareness, for 5 to 15 minutes in everyday life, and 61.7% practiced stretching exercises for 30 to 40 minutes regularly.