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Treatment with warfarin due to atrial fibrillation was paused 3 days prior to CABG. During surgery 3.5 mg/kg of unfractionated heparin was given before cardiopulmonary bypass was initiated resulting in an activated clotting time above 480 s. After cardiopulmonary bypass was finished protamine Pentamorphone sulfate was given until the activated clotting time was below 125 s. In the postoperative period of immobilization 4000 international units of enoxaparin was given once daily. Lifelong postoperative treatment with acetylsalicylic acid as well as patients�� previous anti-coagulation therapy was restarted on the second day after CABG. Statistical Analysis Statistical analyses were performed using the SAS Enterprise Guide statistical software version 4.3. A nominal level of 5% statistical significance (two tailed) was assumed throughout. Categorical variables were presented as percentages and comparison between participants and non-participants was analyzed with the ��2 statistic. If the expected cell count was Selleck LBH589 atrial fibrillation. Additional baseline data for the participants are presented in Table 2. Patient outcomes Postoperatively one participant (no. 94) suffered a clinical stroke (day 0) with light paresis of the upper left extremity. Description of the cerebral MRI-scan for this patient can be viewed in Table 3. The paresis was resolving on day 2. There was no development of neurological symptoms among the other participants. CE-MRA A total of 11 out Adriamycin cell line of 46 participants (24%) had signs of carotid artery plaque (i.e., all carotid stenoses visible on CE-MRA). Three of the participants had bilaterally distributed plaques. Six participants (13%) had significant carotid artery stenosis (i.e., carotid stenosis diameter >50%), and five participants (11%) had significant vertebral artery stenosis. DWI 16 out of 46 participants (35%) had evidence of acute cerebral infarction ranging from