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Differences in proportionate morbidity between 2009 and 2008 in ill returned travellers seen at EuroTravNet core sites were tested with Pearson chi-square or Fisher exact tests. t-Tests were used for continuous variables. A p-value of for travel, risk level and clinical setting Nintedanib in vitro is given in Table?1. The median times from travel to presentation at a clinic was 12?days (in 2008) and 13?days (in 2009) respectively in travellers and 2.4?years (2008 and 2009) in those whose reason for travel was immigration. In both 2008 and 2009, travellers were most likely exposed in sub-Saharan Africa (25.9% and 25.67%, respectively). In 2009, there was a remarkable increase in the proportion of travellers exposed in North America (0.33% in 2008 and 1.83% in 2009) and western Europe (3.26% in 2008 and 4.55% in 2009). The contrary was true for eastern Europe (1.64% in 2008 and 0.86% in 2009), North Africa (4.74% in 2008 and 3.88% in 2009) and South Central Asia (9.77% in CYTH4 2008 and 8.6% in 2009). Country of exposure could not be ascertained in 31.64% and 29.85% of cases in 2008 and in 2009, respectively (Table?1). Region-specific proportionate morbidities are presented in Table?3. Deaths? Two deaths were reported in 2009. The first was a 32-year-old male with chronic hepatitis?B, born in Eritrea but of Sudanese nationality, who died after 6?days of visceral leishmaniasis and sepsis. The second was an 86-year-old male Norwegian with chronic obstructive pulmonary disease and Parkinson��s disease, who died from Acinetobacter sp. pneumonia 4?days after returning from Spain. Three deaths were reported in 2008. Travel-related diseases in Europe? The proportion of patients suffering from respiratory illnesses increased from 7.8% in 2008 to 11% in 2009 (p?this website Most of this increase was attributable to cases in 2009 of pandemic A(H1N1) influenza. Vector-borne disease with potential for re-introduction into Europe.? The number of malaria, dengue and chikungunya cases, considered all together, significantly increased from 507 (7.3%) to 564 (8.8%) (p?