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05. The relationships between changes from rest to exercise in MCA Vmeanversus O2HbC and HHbC were assessed using the Pearson product�Cmoment correlation. Maximal hand-grip force did not differ between conditions SP600125 purchase (control, 282 �� 25 N; Cuff+, 286 �� 23 N; and Cuff-, 288 �� 22 N; P > 0.05; Fig. 2). Mean arterial pressure decreased during hand-grip exercise in the Cuff�C condition, whereas an increase was observed in the other conditions (P MAO exercise in both control (P Table 2 and Figs 2 and 3). In contrast, O2HbC decreased (P increased during hand-grip exercise, whereas no differences were observed between conditions (Table 3). Positive correlations (Fig. 4) were observed between the changes (rest to exercise transition) in both MCA Vmean and beta-catenin inhibitor O2HbC (r= 0.657; P