Twelve Ixazomib Discussion Suggestions

Thirty-two patients were treated twice with mannitol. Simply using cross tabs or logistic regression will therefore give biased parameter estimates and odds ratios. To deal with this problem, a specific linear regression model was used, which is known as the Generalised Estimating Equations (GEE) approach.19 This technique corrects for depending observations by modelling correlations between S6 Kinase subjects. To find out which factors could have prognostic value on the effect of mannitol treatment, a univariate analysis between the effect of mannitol treatment and all possible predicting variables (age, gender, skin temperature, affected extremity, type of CRPS I, smoking behaviour and previous mannitol treatment) was performed first and again using the GEE approach. Correction for possible confounding factors is easily performed in the GEE approach by inserting the confounder as a second independent variable in the model. We used the GEE model with an exchangeable correlation structure to correct for the repeated measurements within one person. Intra-patients correlations coefficients ranged from 0.10 to 0.33 for the several different analyses. Relations were considered click here significant when p?Selleckchem GSK-J4 when p?