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Figure 5 Distribution of NEV. Discussion Findings of this study indicate that WFG LASIK in myopic eyes with high cylinder is safe, efficient, and predictable. Three months postoperatively, 90.3% (n=552) of eyes had MSE within ��0.50 D of intended correction, and 83.8% (n=512) had postoperative UDVA 20/20 or better. There was a statistically significant improvement in CDVA from ?0.04��0.07 logMAR preoperatively to ?0.07��0.06 logMAR 3 months postoperatively. The comparison with other studies is difficult mainly because in most of the studies of myopic astigmatism, there is no differentiation between different degrees of refractive cylinder. Studies summarized in Table 54�C9 present results specifically for myopic eyes with moderate-to-high cylinder. We achieved favorable outcomes in comparison to the literature review. Although the mean preoperative refractive cylinder in our study group is slightly lower than in most of the other studies, Table 4 shows error vector (which essentially equals to the magnitude of residual refractive cylinder) stratified by preoperative cylinder. The highest error vector we achieved was 0.74��0.55 D in the subgroup of eyes with preoperative refractive cylinder between 5.00 D and 6.00 D. Table 5 Literature review of studies presenting results of moderate-to-high myopic astigmatic Bcl-2 inhibitor correction We observed a small, but statistically significant, regression in refractive cylinder between 1-week and 1-month visits (?0.08��0.39 D, P error were longitudinally assessed over a 1-year period following LASIK for moderate-to-high myopic astigmatism. The authors found significant regression in sphere but no statistically significant change in cylinder between 1-week and 1-year exams (mean cylinder ?0.67��0.54 D at 1 week and ?0.63��0.63 D at 1 year).5 The study was conducted on 48 eyes with preoperative refractive cylinder of ?2.74��0.99 D. Similar findings were presented in the study of Hasegawa et al6 where refractive cylinder remained stable up to 12 months postoperatively in patients with moderate-to-high myopic astigmatism. A small change in refractive cylinder in our study showed statistical significance probably due to the large sample size (compared to other studies); however, it would be interesting to evaluate whether there was a further change beyond the 3-month postoperative visit. The vector analysis of refractive cylinder revealed slight undercorrection with the correction ratio (ratio of the magnitude of SIRC to IRC) of 0.92��0.14 at 3 months postoperatively. The mean error of magnitude (arithmetic difference in the magnitudes between SIRC and IRC) was 0.22��0.40 D, and this variable was correlated to the IRC (r=0.26, P