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Interhemispheric differences between homologues areas were determined using also Student's t test. Statistical significance was set at p 0.05). Neuronal density The three analyzed areas displayed differences in the total neuronal density when NeuN-IR cells were counted. These differences were significant as probed by ANOVA (p DNA Damage inhibitor significant. Interhemispheric differences were not determined (Fig. 1). Figure 1. Layer II neuronal subpopulations density in human prefrontal areas 24, 10 and 46 correspond to cortical areas analyzed. Left: Left hemisphere. Right: Right hemisphere. NeuN+/mm2: density of neurons in layer II. PV+/mm2: density of PV-positive neurons ... The three populations of interneurons Pentamorphone (PV, CB and CR) showed significant differences in the following way: values for PV population (p 0.05) showed that this analysis might not lead identify significant differences between areas, which could explain almost 8% of the total variance (Fig. 1). Cell soma area The three analyzed areas showed significant differences in the soma area when NeuN-IR was evaluated and by using ANOVA. Nonetheless, these differences were significant as probed by ANOVA (p LBH589 mouse 24 and the other two ones were significant. Interhemispheric differences were not determined. This parameter analyzed according with the NeuN-IR does not showed significant differences between hemispheres in areas 24 and 46, meanwhile area 10 cell somas showed a significant higher size in the left hemisphere. Student t test did not allow identifies significant differences between hemispheres. However, the area value for the whole cell population (NeuN) showed significant differences in all three areas (p