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Preliminary analyses of nearby posterior sites (PO7/PO8) yielded the same results. The midline and lateral electrodes were analyzed separately for each mean slope time window (270�C330 ms, 400�C460 ms, 550�C750 ms). Previous work found small decreases in P3a latency for non-targets farther from the target location (Golob and Holmes, 2011). Potential latency differences would not affect the analysis here because the mean slope time windows are much larger than any small latency effects. When appropriate, frontal and posterior electrode sites were analyzed separately. To determine whether a significant linear slope was present single sample t-tests were tested relative to zero slope. Clusters composed of ICs included measurements selleck kinase inhibitor of ERPs and ERSPs that were initially assessed using t-tests in sliding windows following stimulus onset. Based on these results significant time and frequency ranges of interest were identified in each cluster, and mean measures within these regions were quantified for each participant. Repeated measure ANOVA was used to analyze the IC ERP activations and ERSP power values within each cluster separately, using factors of target location (?90��, +90��) and angular disparity (45��, 90��, 135��, 180��). Based on previous observations (Golob and Holmes, 2011), we hypothesized a linear relationship across angular locations and therefore report results of linear contrasts within the ANOVA tests. One ERK inhibitor cell line analysis used absolute locations relative to the head, which will be specified below. Results Behavioral results The mean reaction time to targets was 573 ms �� 17 ms with no difference between target locations (?90�� = 579 �� 19 ms; +90�� = 563 �� 18 ms). However, target hit rate was somewhat greater when attending to the ?90�� vs. +90�� target location [t(34) = 2.2, p = 0.03; ?90�� = 80% �� 2%, +90�� = 76% �� 3%]. False alarms to distractors were comparable for the ?90�� vs. +90�� target location (?90�� = 2.5% �� 0.4%, Cisplatin +90�� = 2.5% �� 0.4%). There was a main effect of angular disparity [F(3, 32) = 11.8, p