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To analyze data, descriptive statistics, T-test, U-test, Chi-square, Fisher exact test and SPSS 16 software were used. The significance level of p-value less than 0.05 was applied for all the statistical tests. Results This study was conducted on 240 women, and their demographic details are presented in Table 1. Mean age of participants was 28.26��5.08 years in Akt inhibitor Cyclofem group and 28.63��7.16 in DMPA group. The mean age of marriage in participants was 18.55��3.62 years in Cyclofem group and 19.58�� 3.66 years in DMPA group. In Cyclofem group, the length of marriage was 8.70��4.89 years and 10.37��6.15 in DMPA group with a statistically significant difference between the two groups. Mean age of first conception was 21.12��4.84 years in Cyclofem group and 19.76��4.88 in DMPA group. Mean of gravidity was 2.15��1.22 in Cyclofem group and 1.83��0.96 in DMPA group. Mean of duration of using contraception was 50.32��7.83 months in Cyclofem group and 47.65��6.98 months in DMPA group. Menstruation status in Cyclofem group was regular (85%) www.selleckchem.com/products/ipi-145-ink1197.html but in DMPA group was irregular (46.7%). In Cyclofem group, there were no adverse effects in 84.2% of women, but in DMPA group there were no adverse effects in 60% of women. In Cyclofem group, the level of education was high school diploma in 60% of women, while the level of education was high school diploma in 46.6% of women in DMPA group. In Cyclofem group, 100% of women were Muslim while in DMPA group 97.7% of women were Muslim. Table 1 Distribution of women who used Cyclofem and DMPA by their characteristics Sexual function in women using DMPA was favorite (60.8%) and 65.8% in Oxacillin women using Cyclofem. The difference in sexual function between Cyclofem and DMPA groups was not significant, but in terms of sexual desire and sexual pain, the difference between the groups was significant (p